Impact of Modeling & Simulation in Drug Development
Rosa’s Worldwide Webinar Series fosters the adoption of modeling and simulation by informing a broad audience about the strategic impact it can have on all aspects of research and development.
Since its inception in 2011, this complimentary monthly series has featured select speakers from academia, industry, Rosa client companies, and Rosa itself. The series has drawn many thousands of attendees worldwide from all drug development disciplines.
PLEASE NOTE - ***ALL WEBINARS PRIOR to 2017*** are available by contacting usCLICK HERE
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Sophie Fischer-Holzhausen, PhD, Scientist Systems Pharmacology, ESQlabs GmbH
Sophie Fischer-Holzhausen, PhD, is a Scientist in Systems Pharmacology at ESQlabs. Her work focuses on advancing computational modeling approaches to address questions in women’s health.
In 2019, Sophie graduated with a master’s degree in Biophysics from Humboldt University Berlin. During her studies, she began exploring the intersection between computational science and female physiology, working on a systems biology approach to investigate the regulation of the human menstrual cycle.
After graduation, Sophie got the opportunity to continue working in this field by joining the Institute of Informatics at the University of Bergen, Norway, as a PhD candidate. Supervised by Prof. Susanna Röblitz, she contributed to the development and extension of mathematical models describing the endocrine regulation of the female reproductive system. In early 2023, Sophie submitted her PhD thesis, "A Matter of Timing – A Modeling-Based Investigation of the Dynamic Behavior of Reproductive Hormones in Girls and Women." - just in time to join AstraZeneca as a Pharmacometrician. Her PhD research included studies demonstrating the potential applications of menstrual cycle models in clinical and pharmaceutical settings, as well as methodological advancements in parameterizing complex models despite limited data availability.
In early 2024, she transitioned to ESQlabs, where she now focuses on projects related to female-specific health concerns. Sophie is not only advancing physiologically based kinetic (PBK) modeling strategies but also promotes modeling and simulation to enhance women’s health.
A matter of timing - a modeling investigation of the interplay between reproductive hormones and ovarian follicles
