Publications

Peer Reviewed Journal Publication

Vincent Lemaire, David Bassen, Mike Reed, Roy Song, Samira Khalili, Yi Ting (Kayla) Lien, Lu Huang, Aman P. Singh, Spyros Stamatelos, Dean Bottino, Fei Hua

From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology (QSP) Modeling in Cancer Immunotherapy

Published in Clin Pharmacol Ther. 2022 Oct 25. Online ahead of print.

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Peer Reviewed Journal Publication

Vidya Ramakrishnan, Christina Friedrich, Colleen Witt, Robert Sheehan, Meghan Pryor, Jasvinder K. Atwal, Kristin Wildsmith, Katherine Kudrycki, Seung-Hye Lee, Norman Mazer, Carsten Hofmann, Reina N. Fuji, Jin Y. Jin, Saroja Ramanujan, Michael Dolton, Angelica Quartino

Quantitative Systems Pharmacology Model of the Amyloid Pathway in Alzheimer’s Disease: Insights into the Therapeutic Mechanisms of Clinical Candidates

Published in CPT Pharmacometrics Systems Pharmacology, Online ahead of print.

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Poster

C. Friedrich, R. Sheehan, C.M. Witt, K. Dasika

QSP Model of Aß Accumulation Predicts Different Treatment Effects at Different Stages of Alzheimer’s Disease

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Poster

C. Friedrich, R.B. Moss, R. Baillie, K. Kudrycki, D. Carlo, M. Reed

Higher Fentanyl Exposures Require Higher Doses of Naloxone for Successful Reversals in a Quantitative Systems Pharmacology Model

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Oral Presentation

C. Friedrich, V. Hurez, R. Myers, M. Reed, K. Dasika, K. Kudrycki, R. Sheehan, T. Zhang, G. Gauderat, A. Aussy, L. Chadli, F. Chassereau, S. Fouliard, S. Hubert, E. Desvaux, P. Soret, L. Laigle, P. Moingeon

Predicted efficacy of a pan neutralizing anti interferon-alpha (IFN-α) monoclonal antibody in a virtual systemic lupus erythematosus (SLE) patient cohort using a mechanistic SLE PhysioPD QSP model

Presented by Servier and Rosa at the Quantitative Systems Pharmacology Conference 2022 (QSPC2022), April 2022,

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Poster

C. Friedrich, V. Hurez, R. Myers, M. Reed, K. Dasika, K. Kudrycki, R. Sheehan, T. Zhang, G. Gauderat, A. Aussy, L. Chadli, F. Chassereau, S. Fouliard, S. Hubert, E. Desvaux, P. Soret, L. Laigle, P. Moingeon

Predicted efficacy of a pan neutralizing anti interferon-alpha (IFN-α) monoclonal antibody in a virtual systemic lupus erythematosus (SLE) patient cohort using a mechanistic SLE PhysioPD QSP model.

Presented by Servier and Rosa at the Quantitative Systems Pharmacology Conference 2022 (QSPC2022), April 2022,

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White Paper

William C. Brastow, PhD

Commercializing Life Science Products

Which Product Properties Are Important in Convincing Physicians and Patients to Use My Product? And How to Ask This Question.

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