Peer Reviewed Journal Publication

T Gordi, R Baillie, LT Vuong, S Abidi, S Dueker, H Vasquez, P Pegis, AO Hopper, GG Power, AB Blood

Pharmacokinetic analysis of 14C-ursodiol in newborn infants using accelerator mass spectrometry.

Published in the Journal of Clinical Pharmacology 54(9): 1031-1037, 2014.

Oral Presentation

C Friedrich

Quantitative Systems Pharmacology (QSP) informs in vitro to in vivo translation for PCSK9 antibody.

Presented by Rosa at the American Conference on Pharmacometrics (ACoP), 2014

Peer Reviewed Journal Publication

S Ermakov, P Forster, J Pagidala, M Miladinov, A Wang, R Baillie, D Bartlett, M Reed, TA Leil

Virtual Systems Pharmacology (ViSP) software for simulation from mechanistic systems-level models

Published in Frontiers of Pharmacology 5: 232, 2014


E Kang, S Frey, K Kudrycki, R Kumar, M Dalessandro, A Gupta, X Wang, V Damian-Iordache, T Wilde, C Friedrich, E Hussey

Physiological modeling offers a valuable tool in early drug development for acne targets

Presented by Stiefel and Rosa at Society for Investigative Dermatology (SID), 2014


L Yan, C Friedrich, K Balic, N Ageyeva, S Nicholson, J Connor, N Dimasi, R Baillie, CY Wu, R Faggioni

Quantitative Systems Pharmacology Modeling to Evaluate Clinical Response of an anti-TNFα/anti-Ang2 Bispecific Antibody in Rheumatoid Arthritis.

Presented by MedImmune and Rosa at the American Society of Clinical Pharmacology and Therapeutics Conference 2014


T Yuraszeck, I Singh, M Klinger, MJ Reed, C Friedrich, R Kumar, S Pagano, S Kasichayanula, M Zhu

A population-based approach to systems pharmacology modeling of the effect of blinatumomab (blin) in adult B-precursor ALL patients.

Presented by Amgen and Rosa at American Society for Clinical Pharmacology and Therapeutics (ASCPT), 2014


I Singh, T Yuraszeck, M Klinger, M Reed, C Friedrich, R Kumar, S Pagano, M Zhu

A Systems Pharmacology Model to Characterize the Effect of Blinatumomab in Patients with Adult B-Precursor Acute Lymphoblastic Leukemia (B-All)

Presented by Amgen and Rosa at the American Society of Clinical Phamacology and Therapeutics Conference, 2014


K Kudrycki

Applications of Quantitative Systems Pharmacology Modeling to Support Inflammatory Disease Research

Presented by Rosa at the Society for Melanoma Research (SMR), 2014

Oral Presentation

A Kadambi

Application of Quantitative System Pharmacology Modeling to Translational Research

Presented by Rosa at the 19th North American International, 29th Japanese, Society for the Study of Xenobiotics (ISSX/JSSX) meeting, 2014

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—Mike Reed, PhD, Chief Scientist, PhysioPD
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