Rosa and Merck & Co., Inc. jointly present the PhysioPD™ poster “Alteration of glucose and insulin regulatory networks in Type 2 diabetes mellitus” at Population Approach Group in Europe (2008)

This poster describes a substantial collaboration in which a quantitative PhysioPD model of the (patho)physiological mechanisms and pathways that underlie type 2 diabetes mellitus was developed to characterize the pharmacological and toxicological attributes of single or multiple compound/target pairs. The ultimate goal of the modeling was to identify the impact of altered pharmacokinetics and the pharmacokinetic-pharmacodynamic relationship on target populations and lead optimization. Reference: PAGE 17 (2008) Abstr 1375 []