Enabling QSP and PK/PD workflows using SimBiology and MATLAB: What’s New?
Sietse Braakman, PhDMathWorks
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SimBiology model and code to perform CI and NCA analyses, and optimization using parallel computing.
Drug discovery and development software spans a spectrum of modeling and analysis tools. In this webinar, you will learn new features in SimBiology to help span modeling and simulation workflows from pharmacokinetic (PK) to quantitative systems pharmacology (QSP) modeling. Highlights include:
• Visualizing confidence intervals on parameter estimates to determine whether model parameters are identifiable given a set of data
• Performing non-compartmental analysis (NCA)
• Computing NCA parameters on simulation data to optimize dosing schedules and amounts relative to target PK parameters
• Running numerous model evaluations with cluster computing on the cloud to explore model response to biological variability