Predictive Healthcare Analytics
Joga Gobburu
Professor, University of Maryland
We started our journey as clinical pharmacologists with pharmacokinetics (PK), physiologic-based PK (PBPK) and gradually expanded to time course of pharmacologic effect (pharmacodynamics). Pharmacometrics, as we know it, encompasses disease, drug and trial modeling to support drug development and regulatory decisions. The more mechanistic pharmacometrics approaches such as PBPK and Quantitative Systems Pharmacology (QSP) have had an increased role in drug development to support drug-drug interaction projections, and discovering novel targets. Quantitative clinical pharmacologists have made great strides into drug development, regulatory science, and patient care. The access to digital data, that was previously unavailable, opens new avenues for us. We are at the cusp of a great revolution that can propel us into predictive analytics. A vision for investing in Predictive Healthcare Analytics will be presented to generate a discussion.