QSP - A must have for me! Current state of QSP science and applications as a key Quantitative Medicine approach
Valeriu Damian
Valeriu Damian is a QSP and PBPK consultant with 26 years of experience at GSK, where he led the Systems Modeling and Translational Biology department, overseeing the application of QSP and PBPK from discovery through development. A recognized leader in his field, Valeriu has held influential positions in ISoP and ASCPT, championing the advancement of QSP science. He has made significant contributions to QSP model development and tools, as well as PBPK modeling for inhaled, transdermal, ocular, and long-acting injectable delivery systems.
August 14 Webinar Recording
In this webinar, Dr. Damian revisits the 2017 ROSA webinar “QSP - What’s in it for me?”, which highlighted how Quantitative Systems Pharmacology (QSP) can enhance decision-making from discovery through development. Over the past seven years, QSP has evolved significantly, earning the trust of industry, academia, and regulators, and establishing itself as a cornerstone of Model Informed Drug Discovery and Development (MID3). This talk will delve into the key workflows, challenges, and opportunities in applying QSP, from early target validation to late-stage clinical development, addressing both efficacy and safety.
QSP has evolved alongside other techniques ranging from pharmacometrics approaches to Digital Twin and Model Informed Precision Dosing from sophisticated Machine Learning to Artificial Intelligence, from small molecule to novel modalities and combination therapies. By leveraging these advancements, QSP continues to drive innovation and efficiency in drug development. This webinar will provide insights into the latest applications and future directions of QSP in the rapidly evolving landscape of pharmaceutical research.