Kenneth Locke, CSO of Lithera, Inc., Highlights Rosa Collaboration at Biotech Discussion Group
Kenneth Locke, PhD, Chief Scientific Officer of Lithera, Inc., described the development of Lithera’s LIPO-102 as a pharmaceutical lipoplasty treatement for Grave’s disease and a non-surgical alternative to liposuction. In a collaboration with Rosa, preclinical data was extrapolated to determine First-In-Human dosing that met constraints imposed by Section 505(b)(2) [21 USC §355]. “Rosa’s work allowed us to select the right FIH dose, and trial observations were very close - within 10% of what they predicted. The... modeling also allowed us to titrate directly to a final dose, and saved us significant time and cost...”, stated Dr. Locke.